WHY PATIENTS NEED YOUPfizer’s purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.POSITION SUMMARYAs a Senior Scientist in the Molecular Pharmaceutics group, you will act as a resident pharmaceutical science subject matter expert to influence small molecule early drug candidate selection with respect to drug delivery, bio-performance, and stability. This position will closely collaborate with colleagues across PharmSci as well as with partners in Medicinal Chemistry, Pharmacokinetics & Drug Metabolism, and Clinical Pharmacology. You will be responsible for designing, implementing, and interpreting in vitro, in silico, and in vivo experiments, as well as design of stage appropriate traditional and enabled formulations for preclinical studies. This role will also specialize in formulation and characterization of spray dried dispersions (SDDs). An understanding of drug product development, as well as an understanding of the disease state, drug targets and drug-target mechanisms of action, will help to enable and narrow the definition of the required design elements. In additional to formulation, you will be responsible for material science and physicochemical properties assessments of early drug candidates. This includes laboratory measurements and interpretation of the data to inform manufacturing, bio-performance, and stability development risks.
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